TheraNovis
Background
System Interface

QuantiSpark

FCS Field Diagnosis

QuantiSpark

Technical Specifications

Technology & Products

Featured Product Lineup

Staining and Analysis Solutions for Spatial Proteomics

1. Biomarker Panel

1. Biomarker Panel

  • Development of PD-L1 companion diagnostic panels
  • Development of panels for immune cell and tissue structure analysis
  • Development of 6-marker panels
  • Development of 100+ biomarker panels
2. Antibody Kit

2. Antibody Kit

  • Signal amplification technology for pathological tissue staining
  • Localization and performance enhancement of high-cost existing products
  • Development of next-generation multiplex fluorescence staining kits
  • Development of 9-plex, 12-plex, and 120-plex kits
3. Automated Staining System

3. Automated Staining System

  • Temperature controlled tissue staining system → Compatible with TSA-based staining kits
  • Flow-cell-based tissue staining system → Applicable to DNA barcoding, fluorescence, and chromogenic staining kits
4. Automated Slide Scanner

4. Automated Slide Scanner

  • Automated fluorescence slide scanning system
  • FLIM-based slide scanner (developed by Intact Plus)
  • Compatible with conventional fluorescence slide scanners
5. Data Analysis Platform

5. Data Analysis Platform

  • Tissue and cell segmentation based on deep learning
  • Phenotyping based on cell morphology
  • Spatial analysis for cellular network analysis
  • TIPS and CPS analysis for companion diagnostics

Advanced Multiplex Staining Kits Powered by Proprietary Technology

Next-generation technology enabling simultaneous protein and RNA imaging, optimized for drug discovery and biomarker identification (Hyperplex IF)

* Unprecedented level of data can be obtained from a single tissue slide at a competitive cost.

AstraBCF (up to 120-plex)

AstraBCF (up to 120-plex)

Unlock Unprecedented Data with TSA-Based Technology

Achieve high-sensitivity, multiplex staining and extract deeper insights from a single tissue slide—efficiently and cost-effectively.

Standard

Standard detection

AstraTSA

AstraTSA

  • 10-100x improvement in fluorescence signal sensitivity
  • Minimizes autofluorescence
  • Reduces antibody (Ab) usage to one-fifth of conventional levels
  • Enables simultaneous use of multiple markers
  • Compatible with signal amplification across all immunoassays
  • Supports both chromogenic and fluorescent labeled probes
TSA-Based Kit

TSA-Based Kit

Initially deployed across 30 institutions, including Asan Medical Center, with 20 units supplied to Mayo Clinic
  • Following the development of TSA dyes, 12 spectrally distinct fluorescent TSA dyes were produced.
  • Commercialized staining kits configured in 4-plex, 7-plex, 9-plex, and 12-plex formats using fully validated panels.
  • Achieved over 70% in-house integration through proprietary reagent production.
  • Designed for broad compatibility, enabling easy adoption in laboratories equipped with fluorescence microscopes.
  • Developed autofluorescence removal kits and preprocessing kits for skin cancer fluorescence staining.
Background

An automated staining system (NovaStain™) that saves researchers' time and enhances result reliability

AstraNavi provides an automated tissue staining system optimized for TSA-MIF, based on continuous user feedback.

Temperature Control

Precise thermal management for optimal staining

Fluidic Control

Automated reagent delivery and circulation

User Environment

Optimized workflow for laboratory efficiency

Eliminating Key Workflow Bottlenecks, Achieving Complete Standardization of Staining

Challenges
  • 1. Operator Dependency

    Variability in results increases based on user skill level

  • 2. Lack of Standardization

    High variability across laboratories and operators

  • 3. High Failure Rates and Costs

    Loss of valuable samples and expensive reagents

* Standardizing the staining process determines up to 50% of overall data quality.

By controlling variables in the staining process, we ensure reliable data across the entire workflow

Our Solution
  • 1. Automated Reproducibility

    Automation of multiplex staining processes eliminates user-to-user variability

  • 2. Software-Driven Quality Control

    Ensures consistency through real-time process control and monitoring

  • 3. End-to-End Integration

    Enhances overall quality through seamless connection with downstream analysis

Compared to competitors, delivers higher detection sensitivity, faster processing time, and multiplexing capability—while maintaining strong cost competitiveness

ProductCell DIVECODEXHyperionGeoMxAstraNavi
ManufacturerCytivaAkoyaFluidigmNanoStringTheraNovis
Number of Biomarkers60100374120
Channels54135412 markers / 4 channels
DyeDAPI, Cy2/3/5/7DNA Barcoding AbAb labeled with metal ionsOligo Barcoding Ab12 dyes for antibodies
Validated Antibodies350+ validated Ab160>10096200
Spatial ContextYesYesYesNoYes
Throughput8 plex 1 slide/day35 plex 1 slide/day37 plex/day4 plex 16 slides/day12-plex: 1 slide / 2h, 120-plex: 1 slide / day

Competitive Technology Comparison (Global & Domestic)

Our Solutions

Expert-level spatial analysis reports generated in just a few clicks

Cloud-Based

Access and analyze data anytime, anywhere

Automated Analysis

Automated TIPS & CPS scoring and spatial cellular network analysis

User-Friendly Dashboard

Intuitive UI/UX with automated report generation

AnyPath Dashboard

CHIEF™ Image viewer and data extraction preprocessing software

AnyPath™ Cloud-based automated analysis and reporting platform

AI-Powered Automated Analysis Software

1. Development of machine learning-based analysis technologies for multiplex IHC results

  • Provides solutions that streamline image analysis workflows for digital pathology, and develops AI-driven platforms, 'CHIEF™ & AnyPath™' for fast and accurate image evaluation
  • Development of systems enabling automated tumor region detection and analysis through collaboration with AI companies
Integrated Pathology Diagnostics Platform Workflow

2. Development of automated TPS/CPS analysis methods (AnyPath™ PD-L1)

  • Korean patent granted, PCT application filed, and U.S. patent application submitted
Automated TPS/CPS analysis methods (AnyPath™ PD-L1)

Multiplex Image Analysis Result (6-plex, 120-plex)

Contact Banner

Discover the hidden value of your tissue samples with our Advanced Spatial Proteomics Solution.

Join leading researchers in unlocking the next frontier of precision medicine.